Design, Synthesis And Biological Evaluation Of New Opioid Analgesics Based On Tetrahydro-Β-Carboline Scaffold In Zebrafish (Danio Rerio) Larvae

Alananzeh, Waleed Abdullah Ahmad (2024) Design, Synthesis And Biological Evaluation Of New Opioid Analgesics Based On Tetrahydro-Β-Carboline Scaffold In Zebrafish (Danio Rerio) Larvae. PhD thesis, Universiti Sains Malaysia.

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Abstract

The present study aims to design, synthesise, and evaluate the analgesic activities of THβC derivatives. A database of 25,227 THβC analogues was prepared from structure based virtual screening of the ZINC database for bromine fragments and linking the fragments at the N2 position of the THβC scaffold.

Item Type: Thesis (PhD)
Subjects: R Medicine > RM Therapeutics. Pharmacology > RM300-666 Drugs and their actions
Divisions: Pusat Penyelidikan Dadah dan Ubat-ubatan (Centre for Drug Research) > Thesis
Depositing User: Mr Aizat Asmawi Abdul Rahim
Date Deposited: 04 Nov 2025 08:15
Last Modified: 04 Nov 2025 08:15
URI: http://eprints.usm.my/id/eprint/63170

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