Foo, Lee Kok
(2010)
Ultrasonography findings in
retinopathy of prematurity - a pilot study.
Masters thesis, Universiti Sains Malaysia.
Abstract
1. To describe the fundus findings in different stages of ROP.
2. To determine the ultrasonographic B-scan findings in different stages of
ROP.
3. To determine the association between clinical fundus findings and
ultrasonographic B-scan findings in different stages of ROP. Descriptive cross sectional study. A total of 90 eyes of 47 patients with different stages of ROP were recruited in this study.
All patients’ clinical diagnosis was established by ophthalmoscopic examination. The
ultrasound examinations were performed within 2 days of ophthalmoscopic examination and
clinical diagnosis was masked. All eyes were examined with 10 MHz ultrasound system
with eye closed with instillation a drop of topical anaesthetic. A total of 12 meridians
(position according to clock hour) images of each eye were taken. The images were analyzed
and identified of different ultrasonic features indicative of ROP stages. In this study, 37 eyes in Stage 1, 29 eyes in Stage 2, 18 eyes in Stage 3 and 3 eyes in Stage 4
and 5 respectively were recruited. All ultrasonography stages of ROP were studied. 91.1% of
Stage 1 has negative sign. 3 eyes (9.1%) at stage 1 has stage 2 ultrasound findings. In Stage
2, 58.6% of eyes have ultrasound findings of “shallow retinal thickening and ridge” and
41.4% of eyes have negative sign. 66.7% of eyes at stage 3 showed “broad retinal thickening
and giant ridge”, 5.5% of stage 3 showed stage 2 ultrasound signs and 27.8% of stage 3 has
negative sign. All eyes at stage 4 and 5 have an excellent ultrasonographic detection. The
clinical findings were strongly correlated to ultrasound findings of all five stages in our
study (Pearson R = 0.83,/? <0.001). Ultrasonography features in ROP are readily detected and described especially in Stage 3
ROP and above. Stage 1 ROP showed negative sign of ultrasound. There is high degree of
correlation between the clinical features and ultrasonography features at all stages.
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