Ahmad Helmy, Abdul Karim
(2009)
Study of computed tomography
perfusion in traumatic cerebral
contusion.
Masters thesis, Pusat Pengajian Sains Perubatan.
Abstract
Study of computed tomography perfusion (CTP) in traumatic cerebral contusion Head injury is listed as the sm principle cause of death in Ministry of Health (MOH)
hospitals with percentage of 6.07% (Health Statistics MOH, 2004). The prevalence rate of
cerebral contusion was recorded as 15.0%(Wintermark et al., 2004). Non-enhanced CT
(NECT) brain is a sensitive primary diagnostic tool in the evaluation of patients with head
injury. On NECT brain, pericontusional hypodensity area represents oedema. However, its
perfusion disturbance could not be determined from plain CT scan. CTP provides
information regarding ischaemic injuries related to the trauma and able to determine any
evidence of pericontusional ischaemia. Reduction of perfusion can lead to unfavourable
outcome. This study aims to determine perfusion status of pericontusional hypodensity area and
correlation with clinical outcome. Ten patients involved in motor vehicle accidents (MV A) fulfilled the inclusion and
exclusion criterias and hence enrolled in this study from July 2007 to November 2008 ..
NECT scan of the brain was done on admission to confirm presence of contusion and
followed by CTP. The data were analyzed at the CT workstation. Pericontusion areas were
divided into four sections in relation to distance from the skull. Distance and size of
contusion were measured from NECT scan. The region of interest were drawn based on
hypodensity and CTP colour map. Each parameters of perfusion were produced by the
perfusion software and were analyzed. CTP results were categorized as normal, ischaemia
or infarct Clinical outcome was evaluated using GOS after 6 weeks post trauma.
Actions (login required)
 |
View Item |
