Djokomuljanto, Stanislaus
(2008)
A coparative study of single phot . hjerapy plus white curtains and sigle phototherapy
in term newborns with
hyerrilirubinaemia.
Masters thesis, Pusat Pengajian Sains Perubatan.
Abstract
To determine whether the addition of low-cost reflecting curtain to a standard
phototherapy unit could increase effectiveness of phototherapy for neonatal jaundice. Randomized controlled clinical trial. Level one nursery of the Hospital Universiti Sains Malaysia, Kelantan, Malaysia. Term newborns with uncomplicated neonatal jaundice presenting in the first week of
life. Phototherapy with white curtains hanging from the sides of phototherapy unit (study
group, n=50) was compared with single phototherapy without curtains (control group,
n=47). The primary outcome was the mean difference in total serum bilirubin measured at
baseline and after 4 hours of phototherapy. The secondary outcome was the duration of
phototherapy. The mean (standard deviation) decrease in total serum bilirubin levels after 4 hours of
phototherapy was significantly (p<0.001) higher in the study group [27.62 (25.24)
J.tml/L] than in the control group [4.04 (24.27) J.tml/L]. Cox proportional hazard
regression analysis indicated that the median duration of phototherapy was significantly
shorter in the study group ( 12 hours) than in the control group (34 hours; i change
45.2; p<0.001; hazards ratio 0.20; 95% confidence interval 0.12 to 0.32). No difference
in adverse events was noted in terms of hyperthermia or hypothermia, weight loss, rash,
loose stools or feeding intolerance. Hanging white curtains around phototherapy units significantly increase the efficacy of
phototherapy in the treatment of neonatal jaundice without evidence of increased
adverse effects.
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