Asualingam, Theepa
(2007)
Development And Validation Of HPLC Method For Simultaneous Determination Of Haloperidol And Reduced Haloperidol In Plasma : Application In Pharmacokinetic Study
[RM333.5. T375 2007 f rb].
Masters thesis, Universiti Sains Malaysia.
Abstract
Haloperidol merupakan suatu drug antipsikotik yang tipikal dan secara kimianya daripada kumpulan butirofenon. Suatu kaedah kromatografi cecair berprestasi tinggi yang peka dan selektif dengan pengesan ultra-lembayung telah diperkembangkan bagi penentuan haloperidol dan haloperidol terturun secara serentak di dalam plasma.
Haloperidol is a typical antipsychotic drug that chemically belongs to butyrophenone group. A sensitive and selective reversed-phase HPLC method with ultraviolet detection was developed for the simultaneous determination of haloperidol
and reduced haloperidol in plasma.
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