Al-Akhali, Khaled Mohmmed Ahmed Ali
(2007)
The Application Of Lc-Ms-Ms To Study The Effects Of Fasting, Food And Antacid On The Pharmacokinetics Of Simvastatin In Healthy Malaysian Subjects [RM301.5. K45 2007 f rb].
PhD thesis, Universiti Sains Malaysia.
Abstract
Simvastatin ialah sejenis analog lovastatin dalam bentuk lakton yang digunakan untuk merawat hipekolestrolemia. Simvastatin menurunkan paras plasma kolestrol dengan merencat 3-hidroksi-3-metilglataril-CoA reduktase.
Simvastatin a lactone analog of lovastatin which is used in the treatment of hypercholesterolemia. Simvastatin lowers plasma cholesterol by inhibiting 3-hydroxy-3-methylglutaryl-CoA reductase.
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