Abdullah, Mohd Redzuan (2021) Day And Night Time Packed Red Blood Cells Transfusion Practice Among Adult Patients In Non-emergency Wards At Hospital Universiti Sains Malaysia (Husm) Kelantan. Masters thesis, Universiti Sains Malaysia.
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Abstract
Background: Most of the transfusion services have a policy of strongly discouraging blood administration at night unless for emergency cases. However, blood transfusion at night is still a common practice in most hospitals even in the non-emergency wards. Thus, this study aimed to audit the practice of PRBC transfusion and its compliance towards national transfusion guideline. Methods: This is a cross-sectional study involving a retrospective data collection of 385 adult inpatients who received PRBC transfusion in Hospital Universiti Sains Malaysia (HUSM) from 1st January 2017 to 31st December 2018. The selected patients were grouped into day and night time transfusion. Night time blood transfusion is defined as those who received PRBC between 8.00 pm to 8.00 am. Data for demographics, clinical characteristics, and three time intervals of transfusion process were collected from blood transfusion request form, MyTransfusi online system, and patient case note. Factors associated with night time blood transfusion were analysed using multiple logistic regression. Results: Total PRBC transfusion was 13,090 units. The prevalence of night time PRBC transfusion was 19.3% (2,523 units). Generally, female (56.2%), Malay (93.8%), bloop group O (35.7%), and from the medical discipline (28.6%) were the highest group of patients transfused at night. There were only 44 (39.3%) patients who received night time transfusion classified into acute clinical need group of transfusion indication. Most of the night time PRBC were transfused after 30 minutes issued by the blood transfusion service which were 70 patients (62.5%). Besides, 29 patients (25.9%) for night time group of patients received transfusion beyond four hours limit. Cryoprecipitate was 2.7 times more likely to be transfused at night (adjusted OR= 2.70; 95% CI= 1.04,7.01; P= 0.041). Adverse transfusion reaction was 7.1 times higher risk to develop at night (adjusted OR= 7.07; 95% CI= 1.26,39.71; P=0.026). Conclusion: Even though the practice of the night time PRBC transfusion was low, there was an increased in adverse transfusion reactions during this time and thus potentially increased morbidity and mortality of patients.
| Item Type: | Thesis (Masters) |
|---|---|
| Subjects: | R Medicine |
| Divisions: | Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)) > Thesis |
| Depositing User: | NOR HASHIMY BIN ABDULLAH |
| Date Deposited: | 17 Apr 2026 02:16 |
| Last Modified: | 17 Apr 2026 02:16 |
| URI: | http://eprints.usm.my/id/eprint/63931 |
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