Daoud, Butt Muhammad
(2024)
Cost Of Illness, Health-Related Quality Of Life And Costeffectiveness Analysis Of Pharmacistled
Lifestyle Intervention Among
Diabetes Population In Pakistan.
PhD thesis, Perpustakaan Hamzah Sendut.
Abstract
Diabetes mellitus is a growing public health concern in Pakistan, imposing a
substantial economic burden and negatively affected individuals’ health. Pharmacistled
lifestyle interventions may manage diabetes, but their cost-effectiveness in
Pakistan is unknown. This study aims to evaluates Diabetes cost of Illness, HRQoL,
and pharmacist-led lifestyle treatment cost-effectiveness. Over 12 months, a socially
extensive economic analysis was done. The cost of illness study covered direct, nonmedical,
and indirect diabetes management costs. The societal cost of illness was
calculated. The quantitative study assessed HRQoL with the EQ-5D-5L and diabetesspecific
distress with the DAI-10. Medication behavior and self-management were
examined using the MDKT and DSMQ. A randomized controlled trial examined
pharmacist-led diabetes education. To calculate incremental cost-effectiveness, a
decision-analytic model compared pharmacist-led lifestyle changes to standard
treatment. Pakistani Diabetes Outpatient Clinics provided 1,839 diabetics for the
study. Three districts were selected from each province, afterwards from these districts
only metropolitan cities were selected, clustered sampling approach was used and 150
participants were included from each districts. In Phase 1 over 1,839 Pakistani
outpatient clinic diabetic patients were investigated. Alarmingly, several patients had
uncontrolled blood sugar, requiring improved treatment. The annual total cost of
diabetes care was USD 740.1. The cost covered direct, non-medical, and indirect
diabetes management costs.
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