Synthesis, Characterization, Cytotoxicity, And Antimicrobial Activity Of Azobenzene-Imidazolium Ionic Liquid Crystals

Funmilayo, Babamale Halimah (2023) Synthesis, Characterization, Cytotoxicity, And Antimicrobial Activity Of Azobenzene-Imidazolium Ionic Liquid Crystals. PhD thesis, Universiti Sains Malaysia.

[img]
Preview
PDF
Download (609kB) | Preview

Abstract

Four new series of azobenzene-imidazolium salts were synthesized by azo coupling, followed by alkylation and subsequent quaternization of N-alkylated imidazoles of various chain length with azobenzenes to afford the non-fluorinated (9a-9e), difluorinated (10a-10e) and tetrafluorinated (11a-11e, 12a-12j) salts. The purity of the compounds was confirmed by CHN elemental analysis and their structures were elucidated using the FTIR, 1D and 2D NMR spectroscopies. The liquid crystalline (LC) properties of the salts were studied using the DSC and POM. In vitro cytotoxicity was explored using the MTT assay and their antimicrobial activities were investigated using the disc diffusion method. Smectic A (SmA) phase was observed in almost all compounds.

Item Type: Thesis (PhD)
Subjects: Q Science > QD Chemistry > QD1-999 Chemistry
Divisions: Pusat Pengajian Sains Kimia (School of Chemical Sciences) > Thesis
Depositing User: Mr Aizat Asmawi Abdul Rahim
Date Deposited: 26 Apr 2024 07:15
Last Modified: 26 Apr 2024 07:15
URI: http://eprints.usm.my/id/eprint/60431

Actions (login required)

View Item View Item
Share