Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks

Fitzrol, Diana Noma (2020) Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks. Masters thesis, Pusat Pengajian Sains Perubatan.

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Abstract

Background and Objective Cognitive impairment in patients following TBI is a significant cause of morbidity both to patients and their families. Memory impairment is one of the most common complaint patients and their families have as it impairs patients’ daily function. Current neuroimaging modalities allows us to study the neuronal activation relevant to working memory in patients. Methods Patients who sustained mTBI/ modTBI, between the age of 18 to 65 years old and managed in Hospital Universiti Sains Malaysia were recruited into the study. These patients and a control group underwent fMRI scanning where they concurrently performed n-back tasks of 4 different memory loads. These fMRI scans were performed at 6 to 10 weeks postinjury and at 6 months post-injury. These cohort of subjects also had neuropsychology assessments performed at the same two time period as the fMRI. Results

Item Type: Thesis (Masters)
Uncontrolled Keywords: Brain injuries
Subjects: R Medicine
R Medicine > RC Internal medicine > RC31-1245 Internal medicine
Divisions: Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences) > Thesis
Depositing User: Mr Abdul Hadi Mohammad
Date Deposited: 14 Mar 2023 06:56
Last Modified: 14 Mar 2023 09:09
URI: http://eprints.usm.my/id/eprint/57316

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