Nerve conduction study of the upper limb and lower limb ii 250 subjects. a comparison between age, sex, height, and weight

Awang, Mohamed Saufi (2010) Nerve conduction study of the upper limb and lower limb ii 250 subjects. a comparison between age, sex, height, and weight. Other. Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia. (Submitted)

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Abstract

Introduction: Nerve conduction study (NCS) is an important tool as part of investigating some neurological disorders. NCS can measure both motor and sensory velocities. There are specific personal factors that can influence the nerve velocity which include age ,sex , height and weight. Objectives: The aim of this study was to investigate the conduction velocities of nerves both in the upper limb and lower limb. The other aim of this study was to observe the influence of specific personal factors like age, sex, height and weight on nerve conduction velocities (NCVs). Material and Method: Two hundred fifty healthy subjects were recruited in this study. They were mainly hospital staffs. The subjects were excluded if they have any neuromuscular disorders or any diseases that can have direct or indirect effect on nerve function such as diabetes or carpal tunnel syndrome. The subjects were divided into different age, height and weight (expressed as body mass index or BMI) groups. The nerves that were tested include: median and ulnar nerves for the upper limb (both motor and sensory velocities) and common peroneal (motor velocity) and sural nerves (sensory velocity) for the lower limb. Surface electrodes were used. The temperature in the laboratory was kept constant above 27 ° C. The targeted nerve was suprarnaximally stimulated using square wave with a duration of 0.2ms and the action potential was picked up by the recording electrodes. The length of each nerve was estimated with a flexible measuring tape. Nerve velocities (rnls) were calculated and documented. Results: Of 250 subjects, 137 were male and 113 were female. The mean age, height and BMI were 34.46 ± 10.79 years, 159.47 ± 8.53 (em) and 23.99 ± 4.20 (kglm2 ). Reduction in NCVs in median, ulnar, common peroneal and sural nerves across different age. Slowing ofNCV was seen only in common peronei nerve across different height groups. There were reduction in NCVs of median, ulnar (motor component), common peroneal and sural nerves as BMI increased. Conclusion: In conclusion, our results showed that age has great influence on nerve velocities. We observed reduction in NCVs as the age increased in median and ulnar nerves (upper limb) and common peroneal plus sural nerves (lower limb) . However, mixed trend ofNCVs were seen across different height and body mass index groups

Item Type: Monograph (Other)
Uncontrolled Keywords: Nerve conduction study
Subjects: R Medicine
Divisions: Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences) > Monograph
Depositing User: Mr Abdul Hadi Mohammad
Date Deposited: 12 Sep 2022 04:09
Last Modified: 12 Sep 2022 04:09
URI: http://eprints.usm.my/id/eprint/54576

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