Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models

Hassan, Rahimah (2021) Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models. PhD thesis, Universiti Sains Malaysia.

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Abstract

The current study was designed to test the ability of mitragynine to attenuate behavioural signs of morphine-withdrawal in a rat model in comparison to methadone and buprenorphine. A six-day treatment with escalating dose of morphine (10-50 mg/kg, i.p.) induced profound withdrawal signs for 16 days.

Item Type: Thesis (PhD)
Subjects: R Medicine > RM Therapeutics. Pharmacology > RM300-666 Drugs and their actions
Divisions: Pusat Penyelidikan Dadah dan Ubat-ubatan (Centre for Drug Research) > Thesis
Depositing User: Mr Aizat Asmawi Abdul Rahim
Date Deposited: 27 Jul 2022 07:44
Last Modified: 27 Jul 2022 07:44
URI: http://eprints.usm.my/id/eprint/53633

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