In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration

Tan, Florence Hui Ping (2020) In Vitro And In Vivo Study On The Identification Of Compounds That Alleviate Aβ42 Associated Neurodegeneration. PhD thesis, Universiti Sains Malaysia.

Preview

PDF Download (371kB) | Preview

Abstract

Alzheimer’s disease (AD) is the most common type of neurological disorder globally. Its mechanism includes the distinctive aggregation of extracellular senile plaques made up of amyloid-beta (Aβ) in the brain. Among the Aβ isomers secreted in the brain, Aβ42 is the most neurotoxic and aggressive. Regardless of the immense research on AD, the full pathogenesis of this disease remains unknown. The main aim of this study was to identify compounds that are able to alleviate Aβ42’s negative effects.

Item Type:	Thesis (PhD)
Subjects:	R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions:	Pusat Pengajian Sains Farmasi (School of Pharmacy) > Thesis
Depositing User:	Mr Aizat Asmawi Abdul Rahim
Date Deposited:	15 Jul 2022 08:33
Last Modified:	15 Jul 2022 08:33
URI:	http://eprints.usm.my/id/eprint/53394

Actions (login required)

View Item