Atan, Edinur Hisham
(2006)
Classification of Haplogroup C and Haplogroup D in Modern Malay and
Chinese population of Peninsular Malaysia.
Other.
Universiti Sains Malaysia.
(Submitted)
Abstract
Mitochondrial DNA analysis is carried out for 45 samples from modem Malay and 44
samples from modem Chinese populations of Peninsula Malaysia. The mitochondrial
DNA coding region variation of these samples was examined using restriction fragment
length polymorphism (RFLP) method. From the analysis of Alu I site gain nucleotide
position 10397, 37.78% of modem Malay population of peninsular Malaysia belongs to
superhaplogroup M while 4 7. 73% of the modem Chinese belong to superhaplogroup M.
Superhaplogroup M is further divided into several haplogroup, which are defined by the
presence of specific RFLP markers. Haplogroup C and Haplogroup D are determined by
the presence of Alu l restriction site at the nucleotide position 13 262 and the absence of
Alu 1 restriction site at the nucleotide position 5 176. For Modem Malay population, only
8.89% of the sample belongs to the haplogroup D while none belong to the haplogroup C.
For modem Chinese population of peninsular Malaysia, 4.65% of the samples belong to
haplogroup C and 6.82% of the samples belong to the haplogroup D.
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