Mokhtar, Kasmawati
(2006)
Assessing the ability of acidulated fluoride solutions to etch glass-based restorative materials - a pilot study.
Masters thesis, Universiti Sains Malaysia.
Abstract
Topical fluorides have been used widely in dentistry for over fifty years, and are credited
with having contributed greatly to the marked decline in caries prevalence recorded in most
industrialized countries over the last three decades (Fejerskov, 1981 ). A wide variety of
forms of topical fluoride have been developed in an effort to provide differing modes of
action in caries control. For example, the low concentrations of fluoride in dentifrices and
mouth rinses have been designed to provide prophylactic protection against caries across
the population, though are effective only to a limited degree. More advanced rates of
caries development have lead to the formulation of high fluoride concentration gels and
varnishes subject to professional application on prescription. One such gel containing
sodium fluoride in an acidulated base (called acidulated phosphate fluoride or APF), was
widely used until it was found to etch glass-based restorative materials. Yet, such a
formulation has been shown to provide a much higher level of fluoride uptake into tooth
structure, (Pai, 1995) and to protect against strong acidic challenges such as dental erosion
than its neutral counterpart. The studies to evaluate the latter effect were by Jones et al
(2002) and Mok et al (2001) who reported the reduction in the loss of enamel surface to a
significant extent with the application of acidulated topical fluoride gel prior to simulated
endogenous and exogenous acid exposure.
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