Kamarudin, Mohd Nazlin
(2018)
Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI.
Masters thesis, Universiti Sains Malaysia.
Abstract
Background: Diffusion tensor imaging is a standard method for evaluation of
musculoskeletal pathology. The objective of this study is to determine the optimal
b-value and number of diffusion direction for diffusion tensor imaging of rotator cuff
muscles in healthy subjects on 3.0 Tesla MRI.
Methodology: 38 healthy volunteers were included in this prospective study. Diffusion
tensor imaging (DTI) of the rotator cuff muscles (subscapularis, supraspinatus and
infraspinatus muscles) was performed with single-shot spin-echo echo-planar imaging
sequences in 16 and 32 diffusion directions. Three different b-values were selected for
each diffusion direction: b-value 400 s/mm2, 600s/mm2 and 800s/mm2. Signal to noise
ratio (SNR) was measured in each muscle at different b-values and number of diffusion
direction, and average SNR were calculated. Statistical analysis was performed with
one-way ANOVA and paired t-test. Mean and standard deviation were obtained for each
DTI parameters, and level of significance was determined (p < 0.05).
Results: The signal to noise ratio was highest for all three muscles at b-value 400s/mm2
(subscapularis, 40.255; supraspinatus, 38.203; and infraspinatus, 48.232) followed by
b-value 600s/mm2 and 800s/mm2. The use of 32 number of diffusion directions had
shown to improve SNR value compared to 16 diffusion directions (P<0.05).
Conclusions: The optimal combination of b value and number of diffusion directions in
DTI of rotator cuff muscles on 3.0 Tesla MRI is 400s/mm2 and 32 directions
respectively.
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