Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis

Bukari, Bakhtiar Affendi (2017) Generation And Characterisation Of RNA Aptamers Against ESAT6 Protein From Mycobacterium Tuberculosis. Masters thesis, Universiti Sains Malaysia.

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Abstract

Aptamers are chemical ligands made up of short nucleotides sequences that are able to bind to target proteins with high affinity and specificity. They are generated using a process called Systemic Evolution of Ligands via Exponential Enrichment (SELEX). Due to their chemical stability and high specificity against the target, aptamers have the potential to become very useful biological tools. The 6 kDa Early Secretory Antigenic Target, or ESAT6, is a secretory protein produced by Mycobacterium tuberculosis and is thought to be a major player in mycobacterial pathogenesis.

Item Type:	Thesis (Masters)
Subjects:	R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research
Divisions:	Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)) > Thesis
Depositing User:	ASM Ab Shukor Mustapa
Date Deposited:	10 Sep 2019 02:42
Last Modified:	10 Sep 2019 02:42
URI:	http://eprints.usm.my/id/eprint/45354

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