Hamdan, Mohamad Azlan
(2017)
Quality of life in children with bronchial asthma in Institut Pediatrik Hospital Kuala Lumpur (IPHKL).
Masters thesis, Universiti Sains Malaysia.
Abstract
Background: Asthma is a public health problem that adversely affects different
aspects of quality of life (QoL). Childhood asthma is a common chronic disease
affecting children worldwide.
Objective: To measure the quality of life in children with bronchial asthma who
were admitted to the ward due to asthma exacerbation and those who attended
general paediatric clinic for follow up in Institut Pediatrik Hospital Kuala Lumpur.
Methods: In this cross-sectional observational study, 105 children with
physician diagnosed bronchial asthma (57 children attended clinic for follow up
and 48 children admitted for asthma exacerbation) were evaluated to measure
quality of life and were administered paediatric asthma quality of life
questionnaire (PAQLQ).
Results: There were 75 boys and 30 girls, age ranged between 7 to 12 years
with mean of 8.9 ± 1.5 years. For asthmatic children that were admitted to the
ward for exacerbation, the mean age was 8.4 ± 1.2 years and for the asthmatic
children who attended the clinic for follow up, the mean age was 9.4 ± 1.6
years. Asthmatic children that were admitted to the ward for exacerbation had
moderate impairment in their quality of life as the overall mean score was only
4.0 ± 0.6. The mean score of the quality of life in the symptoms, emotionalfunction and activity limitation domains were 3.7 ± 0.7, 4.4 ± 0.8 and 4.0 ± 0.8
respectively. Children with bronchial asthma who attended the general clinic for
follow up had better overall mean score in their quality of life which was 5.9 ±
1.1. This showed that they only had minimal impairment in their quality of life.
Meanwhile, the mean score of the quality of life in the symptoms, emotional
function and activity limitation domains were 5.8 ± 1.2, 6.0 ± 1.0 and 5.8 ± 1.2.
There was no difference of the quality of life score among children with
bronchial asthma that had the disease less than 3 years duration and for 3
years and more for the both groups of these asthmatic children. Similarly, there
was no difference of the quality of life score among asthmatic children who has
normal BMI with asthmatic children who were overweight to obese.
Conclusion: Childhood asthma had significant adverse effects on the quality of
life of the affected children particularly among asthmatic children that were
admitted for acute exacerbation.
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