Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi

Kumar, Thiviyaa M. Othaya (2014) Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi. Masters thesis, Universiti Sains Malaysia.

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Abstract

Non-protein-coding RNAs (npcRNAs) are RNA molecules that do not encode for proteins but are involved in modulating a myriad of cell regulatory processes, including bacterial drug resistance mechanisms. In this study, a novel npcRNA, StyR-3; discovered from the genome of S. Typhi was selected for further characterization via bioinformatics and experimental-based approaches. This 144-nt intergenic npcRNA is located in the ramRA regulon of S. Typhi Ty2. The bioinformatics-based characterization showed that it is highly conserved among Salmonella species; besides having a stable secondary structure as was predicted by LocaRNA software.

Item Type:	Thesis (Masters)
Subjects:	R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research
Divisions:	Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)) > Thesis
Depositing User:	ASM Ab Shukor Mustapa
Date Deposited:	26 Jul 2019 01:25
Last Modified:	26 Jul 2019 01:25
URI:	http://eprints.usm.my/id/eprint/45075

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