Kaniappan, Priyatharisni
(2015)
Development Of A Nucleic Acid Amplification Test For The Detection Of Mycobacterium Tuberculosis.
Masters thesis, Universiti Sains Malaysia.
Abstract
Tuberculosis is one of the common infectious diseases in Malaysia, caused by the airborne pathogen, Mycobacterium tuberculosis. Due to the infectious nature of the disease, diagnostic-based detection of Mycobacterium tuberculosis is vital for effective disease management, surveillance, epidemiological purpose and for the administration of a prompt treatment. Current diagnostic methods rely on smear microscopy and culture method; however these strategies suffer from several pitfalls. This shifts the attention
towards the nucleic-acid based detection of M. tuberculosis, which requires the identification of suitable nucleic acid target as the diagnostic marker.
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