Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts

Ali Antisha, Rabyah B. (2012) Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts. Masters thesis, Universiti Sains Malaysia.

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Abstract

The fruit of Phaleria macrocarpa is used in traditional medicine in Indonesia and the eastern part of Malaysia, as a remedy for the management of diabetes mellitus. This study was therefore carried out to investigate the antidiabetic activity of this fruit in normal and streptozotocin (STZ) -induced diabetic rats. The pulverized dried fruits were sequentially extracted in petroleum ether, methanol and water. None of the extracts (1 g/kg) exerted an effect on blood glucose of normal rats. The methanol and water extracts significantly inhibited the rise of blood glucose after glucose loading in intra-peritoneal glucose tolerance tests (IPGTT) in normal rats.

Item Type: Thesis (Masters)
Subjects: R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: Pusat Pengajian Sains Farmasi (School of Pharmacy) > Thesis
Depositing User: ASM Ab Shukor Mustapa
Date Deposited: 05 Jul 2019 02:26
Last Modified: 05 Jul 2019 02:26
URI: http://eprints.usm.my/id/eprint/44884

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