Qaid, EYA and Zakaria, R and Sulaiman, SF and Yusof, NA Mohd and Shafin, Nazlahshaniza and Othman, Zahiruddin and Ahmad, AH and Aziz, CB Abd (2017) Insight into potential mechanisms of hypobaric hypoxia–induced learning and memory deficit – Lessons from rat studies. Human and Experimental Toxicology, 36 (12). pp. 1-11. ISSN 0960-3271 (Submitted)
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Abstract
Impairment of memory is one of the most frequently reported symptoms during sudden hypoxia exposure in human. Cortical atrophy has been linked to the impaired memory function and is suggested to occur with chronic high-altitude exposure. However, the precise molecular mechanism(s) of hypoxia-induced memory impairment remains an enigma. In this work, we review hypoxia-induced learning and memory deficit in human and rat studies. Based on data from rat studies using different protocols of continuous hypoxia, we try to elicit potential mechanisms of hypobaric hypoxia–induced memory deficit.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Divisions: | Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences) > Article Zoom Profil Pakar (Expert Profile) > Zahiruddin Othman (Medical Sciences) |
| Depositing User: | Administrator Automasi |
| Date Deposited: | 28 May 2019 09:09 |
| Last Modified: | 28 May 2019 09:09 |
| URI: | http://eprints.usm.my/id/eprint/44405 |
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