Othman, Zahiruddin and Zakaria, Rahimah and Hussain, Nik Hazlina Nik and Hassan, Asma' and Shafin, Nazlahshaniza and Al-Rahbi, Badriya and Ahmad, Asma Hayati (2015) Potential Role of Honey in Learning and Memory. Medical Sciences, 3 (2). pp. 3-15. ISSN 2076-3271
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Abstract
The composition and physicochemical properties of honey are variable depending on its floral source and often named according to the geographical location. The potential medicinal benefits of Tualang honey, a multifloral jungle honey found in Malaysia, have recently been attracting attention because of its reported beneficial effects in various diseases. This paper reviews the effects of honey, particularly Tualang honey, on learning and memory. Information regarding the effects of Tualang honey on learning and memory in human as well as animal models is gleaned to hypothesize its underlying mechanisms. These studies show that Tualang honey improves morphology of memory-related brain areas, reduces brain oxidative stress, increases brain-derived neurotrophic factor (BDNF) and acetylcholine (ACh) concentrations, and reduces acetylcholinesterase (AChE) in the brain homogenates. Its anti-inflammatory roles in reducing inflammatory trigger and microglial activation have yet to be investigated.
| Item Type: | Article |
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| Uncontrolled Keywords: | Tualang honey; learning; memory; BDNF; ACh; AChE |
| Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Divisions: | Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences) > Article Zoom Profil Pakar (Expert Profile) > Zahiruddin Othman (Medical Sciences) |
| Depositing User: | Administrator Automasi |
| Date Deposited: | 13 May 2019 08:16 |
| Last Modified: | 13 May 2019 08:16 |
| URI: | http://eprints.usm.my/id/eprint/44322 |
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