The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells

Ahmed, Nor Amira Khurshid (2018) The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells. Masters thesis, Universiti Sains Malaysia.

[img]
Preview
PDF
Download (1MB) | Preview

Abstract

Eurycoma longifolia Jack (Tongkat Ali) is one of the most popular traditional plants found in the tropical rainforest of Southeast Asia, especially in Malaysia and Indonesia. Although E. longifolia is widely used as traditional medicine, little is understood of the in vitro effect on Leydig cells; the testosterone-producing cells. Therefore, the effect of a standardised E. longifolia extract (F2) and pure compound, eurycomanone (EN) on the productions of testosterone, estrogen and aromatase in mouse Leydig cells were determined in this study, whereby the Formestane (FM) was used as a positive control. The effect of F2, EN and FM on the cell viability was first determined using MTT assay.

Item Type: Thesis (Masters)
Subjects: R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research
Divisions: Institut Penyelidikan Perubatan Molekul (Institute for Research in Molecular Medicine INFORMM) > Thesis
Depositing User: ASM Ab Shukor Mustapa
Date Deposited: 20 Mar 2019 07:03
Last Modified: 12 Apr 2019 05:24
URI: http://eprints.usm.my/id/eprint/43710

Actions (login required)

View Item View Item
Share