Ibrahim, Kansaa A.
(2010)
A Pharmacoepidemiological
Evaluation Of Glycaemic Control
Among Diabetes Patients Receiving
Different Treatment Regimens At
Penang General Hospital.
Masters thesis, Universiti Sains Malaysia.
Abstract
Generally, type 2 diabetes mellitus cannot be managed with a single drug or
lifestyle changes alone; therefore, adding anti-diabetic agents or increasing the dose is
recommended to control the disease progression. This study aimed to evaluate the antidiabetic
drugs used at Penang General Hospital in relation to the clinical outcomes of the
disease management and to determine the proportions of diabetic patients who achieved
the target levels. The association between diabetes duration and each of: treatment
strategies, number of complications, comorbidities and clinical outcomes was also
evaluated. This was a cross-sectional retrospective observational study involving 1014
patients with type 2 diabetes mellitus who attended the outpatient diabetes clinic at the
Penang General Hospital in Malaysia. Each patient’s medical record from 2005 to 2007
was reviewed. The primary and secondary clinical outcomes for treatment of diabetes
that are recommended to be monitored include fasting plasma glucose, haemoglobin
A1c (HbA1c), blood pressure (BP) and the lipid profile. All the collected data were
analysed using the SPSS (version 15.0) software package (SPSS Inc., Chicago, IL) and
Microsoft Excel.
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