Bakar, Suhaili Abu and Rosli, Rozita and Chong, Pei Pei and Rahman, Sabariah Abdul and Awidat, Shaban K. and Badri, Karen A.
(2004)
Application of comparative genomic hybridization and fluorescence in situ hybridization on human glioma cell lines treated with bis[S-methyl-β-N-(2-furylmethylketone) dithiocarbazato] cadmium(II).
In:
The 4th Annual Seminar of National Science Fellowship NSF 2004 Proceedings.
Penerbit Universiti Sains Malaysia, Pulau Pinang, Malaysia, pp. 219-224.
Abstract
Gliomas are the most common primary tumors which arise from cells of the brain itself rather than metastazing to the brain from another location in the body. It can be slow growing (low grade, grades 1 and 2) or rapidly growing (high grade, grades 3 and 4). For instance, diffuse and fibrillary astrocytomas are divided histopathologically into three grades of malignancy: World Health Organization (WHO) grade II astrocytomas, WHO grade III anaplastic astrocytoma and WHO grade IV glioblastoma multiforme (GBM) (Otto, 2001).
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