Ismail, Azlini
(2015)
Pharmacological Evaluation On The
Effect Of Syzygium Polyanthum (Wight)
Walp. Leaves Extract On Rat’s Blood
Pressure And Related Parameters.
PhD thesis, Universiti Sains Malaysia.
Abstract
Daun Syzygium polyanthum (Wight) Walp. var. Polyanthum telah digunakan
secara tradisional oleh masyarakat Melayu sebagai rawatan alternatif untuk penyakit
darah tinggi. Bukti saintifik yang menyokong penggunaan tradisional ini masih
terhad. Kajian ini menyiasat kesan ekstrak air (AESP) dan ekstrak “residual”
metanol (met-AESP) bagi daun S. polyanthum ke atas tekanan darah tikus dan
parameter berkaitan.
Syzygium polyanthum (Wight) Walp. var. Polyanthum leaves are
traditionally consumed by the Malays as an alternative treatment for hypertension.
However, the scientific evidence to support this claim is scarcely reported. The
present study investigated the effects of aqueous (AESP) and residual methanolic
extracts (met-AESP) of S. polyanthum leaves on rat’s blood pressure and related
parameters. Both extracts were orally administered on Wistar-Kyoto (WKY) and
Spontaneously Hypertensive rats (SHR), then systolic blood pressure (SBP) were
monitored within 24 hours.
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