Effect Of Exogenously Administered Hydrogen Sulphide (H2S) On Plasma Concentration Of Nuclear Factor-Kappa B (Nf-Kb) And Intercellular Adhesion Molecule-1 (Icam-1) In A Rat Model Of Renal Ischemia Reperfusion Injury

Ul Haq Hashmi, Syed Fayaz (2017) Effect Of Exogenously Administered Hydrogen Sulphide (H2S) On Plasma Concentration Of Nuclear Factor-Kappa B (Nf-Kb) And Intercellular Adhesion Molecule-1 (Icam-1) In A Rat Model Of Renal Ischemia Reperfusion Injury. Masters thesis, Universiti Sains Malaysia.

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Abstract

Kajian ini menyelidik kesan pemberian penderma hidrogen sulfida (H2S), sodium hidrosulphida (NaHS) secara eksogenous ke atas kepekatan nuklear faktor kappa-B (NF-kB) dan molekul-1 intersel (ICAM-1) dalam kecederaan iskemia reperfusi ginjal di dalam tikus normotensif Wistar Kyoto (WKY) tanpa kegagalan ginjal (NRF) dan dengan kegagalan ginjal (RF) serta hipertensi aruhan L-nitro-arginin-methil-ester (L-NAME) di dalam tikus tanpa kegagalan ginjal (NRF) dan dengan kegagalan ginjal (NRF) The present study investigated the effect of exogenous administration of hydrogen sulphide (H2S) donor, sodium hydrosulphide (NaHS) on the concentration of nuclear factor kappa-B (NF-kB) and inter cellular adhesion molecule-1 (ICAM-1) in renal ischemia reperfusion injury in normotensive Wistar Kyoto (WKY) non-renal failure (NRF) and renal failure (RF) rats as well as L-nitro-arginine-methyl-ester (L-NAME) induced hypertensive NRF and RF rats.

Item Type:	Thesis (Masters)
Subjects:	R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions:	Pusat Pengajian Sains Farmasi (School of Pharmacy) > Thesis
Depositing User:	Mr Erwan Roslan
Date Deposited:	01 Feb 2018 03:54
Last Modified:	12 Apr 2019 05:25
URI:	http://eprints.usm.my/id/eprint/38631

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