Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression

Yi, Fan Teah and Abduraman, Muhammad Asyraf and Amanah, Azimah and Adenan, Mohd Ilham and Sulaiman, Shaida Fariza and Mei, Lan Tan (2017) Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression. Data in Brief, 14. pp. 584-591. ISSN 2352-3409

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Abstract

The data presented in this article are related to the research article entitled “The effects of deoxyelephantopin on the cardiac delayed rectifier potassium channel current (IKr) and human ether-a-go-go-related gene (hERG) expression” (Y.F. Teah, M.A. Abduraman, A. Amanah, M.I. Adenan, S.F. Sulaiman, M.L. Tan) [1], which the possible hERG blocking properties of deoxyelephantopin were investigated. This article describes the construction of human embryonic kidney 293 (HEK293) cells overexpressing HERG potassium channel and verification of the presence of hERG mRNA and protein expression in this recombinant cell line.

Item Type: Article
Subjects: Q Science > QH Natural history > QH1 Natural history (General - Including nature conservation, geographical distribution)
R Medicine > RK Dentistry > RK1-715 Dentistry
Divisions: Pusat Pengajian Sains Kajihayat (School of Biological Sciences) > Article
Depositing User: Mr Noorazilan Noordin
Date Deposited: 30 Jan 2018 08:31
Last Modified: 30 Jan 2018 08:31
URI: http://eprints.usm.my/id/eprint/38611

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