Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part of Euphorbia hirta L.

Perumal, Shanmugapriya and Mahmud, Roziahanim and Pillai Piaru, Suthagar and Wei, Cai Lee and Ramanathan, Surash (2013) Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part of Euphorbia hirta L. Journal of Chemistry, 2013 (983253). pp. 1-6. ISSN 2090-9063

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Abstract

Euphorbia hirta is a well-known ethnomedicinal plant with diverse biological activities.The aim of the present study is to investigate the antiradical activities of various solvent extracts of the aerial part of E. hirta as well as to determine the possible cytotoxicity of these extracts. The aerial part of E. hirta was extracted with different solvent systems in order to increase polarity. The solvents used were hexane, dichloromethane (DCM), ethyl acetate (EA), ethanol (EtOH), and methanol (MeOH). The contents of total phenols and total flavonoids were analyzed byUVspectrophotometry, whereas the potential free radical-scavenging activities of the extracts were evaluated using the stable free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH), the

Item Type:	Article
Subjects:	R Medicine > RM Therapeutics. Pharmacology > RM300-666 Drugs and their actions R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions:	Pusat Pengajian Sains Farmasi (School of Pharmacy) > Article Pusat Penyelidikan Dadah dan Ubat-ubatan (Centre for Drug Research) > Article Zoom Profil Pakar (Expert Profile) > Surash A/L Ramanathan (Drug Research)
Depositing User:	Mr Noorazilan Noordin
Date Deposited:	11 Jan 2018 06:13
Last Modified:	11 Jan 2018 06:13
URI:	http://eprints.usm.my/id/eprint/38343

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