Mohd Noor, Nor Haznita
(2002)
Fasting plasma glucose as a screening test for gestational diabetes mellitus : a hospital-based, cross sectional study of 370 antenatal patients in Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia, 1999-2000.
Masters thesis, Universiti Sains Malaysia.
Abstract
Objektif:
Mengkaji glukos plasma berpuasa (fasting plasma glucose) sebagai ujian
penyaringan bagi penyakit kencing manis ketika mengandung (gestational diabetes
mellitus). Objektif selanjutnya adalah untuk menentukan taburan demografi bagi
penyakit kencing manis ketika mengandung dan menilai pecahan penyakit ini yang
dapat dikesan melalui saringan selektif menggunakan faktor sejarak
Metodologi:
Kajian bersilang telah dijalankan di Hospital Universiti Sains Malaysia (HUSM),
Kubang Kerian, Kelantan dari bulan Julai 1999 hingga bulan Oktober 2000. Data
asas diambil daripada 461 pesakit yang bersetuju mengambil bahagian di dalam
kajian ini, yang mana umur kandungannya tidak melebihi 28 minggu dan tidak
mempunyai penyakit kencing manis sebelum ini. Ujian glukos piawai 2-jam 75-g telah
dijalankan ke atas 370 pesakit. Penyakit kencing manis semasa mengandung dan
subkategorinya iaitu kencing manis dan gangguan toleransi terhadap glukos semasa
mengandung telah didefinasikan oleh mengikut 'Definition, Diagnosis and
Classification of Diabetes Mellitus and its Complications. Part 1 :Diagnosis and
Classification of Diabetes Mellitus Provisional Report of a WHO Consultation'. Ciriciri
saringan glukos plasma berpuasa dikaji melalui kiraan sensitiviti dan spesifisiti
dengan 'receiver operator characteristic curves'.
Objective:
To evaluate fasting plasma glucose as a screening test for gestational diabetes mellitus.
Further objectives were to determine demographic distribution of gestational diabetes
mellitus and to assess the proportions of gestational diabetes mellitus picked up by
selective screening using historical risk factors alone.
Methods:
A hospital-based, cross-sectional study was carried out at University Hospital,
Universiti Sains Malaysia (HUSM), Kubang Kerian, Kelantan, from July 1999 till
October 2000. Baseline data from 461 women who agreed to participate in the study
with gestational ages less than 28 weeks and no previous diagnosis of diabetes were
collected. A standardized 2-h 75-g oral glucose tolerance test was performed in 370
women. Gestational diabetes and its subcategories-diabetes and gestational impaired
glucose tolerance-were defined according to the Definition, Diagnosis and
Classification ofDiabetes Mellitus and its Complications. Part !:Diagnosis and
Classification of Diabetes Mellitus Provisional Report of a WHO Consultation.
Screening properties of fasting plasma glucose were evaluated by calculating
sensitivity and specificity with receiver operator characteristic curves.
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