Cell-Penetrating Antibodies For Targeting Hiv-1 P24 Capsid Protein

Teow , Sin Yeang (2015) Cell-Penetrating Antibodies For Targeting Hiv-1 P24 Capsid Protein. PhD thesis, Universiti Sains Malaysia.

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Abstract

Protein kapsid p24 memainkan peranan yang penting dalam peringkat awal dan akhir replikasi HIV. Justeru, kapsid HIV-1 dianggap sebagai sasaran penting dalam pembangunan ubat terapi baharu untuk merawat HIV/AIDS. The capsid protein plays seminal roles in both early and late stages of the HIV replication cycle. Hence, HIV-1 capsid protein is considered an important target for developing novel drugs to treat HIV/AIDS. Capsid molecule (CA)-targeting peptide inhibitors (CAP-1, CAI and NYAD-1) have been reported to disrupt the capsid protein functions in HIV-infected cells.

Item Type:	Thesis (PhD)
Subjects:	R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research
Divisions:	Institut Penyelidikan Perubatan Molekul (Institute for Research in Molecular Medicine INFORMM) > Thesis
Depositing User:	Mr Firdaus Mohamad
Date Deposited:	10 Jan 2017 06:48
Last Modified:	12 Apr 2019 05:25
URI:	http://eprints.usm.my/id/eprint/31512

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