Abdul Hamid, Fitrah Mujahidah
(2015)
The Effect Of Otub1 Overexpression On Human Cervical Cancer Hela.
Masters thesis, Universiti Sains Malaysia.
Abstract
Protein ubiquitinasi adalah proses regulasi yang mengawal kebanyakan mekanisma fisiologi dan patologi dan yang melibatkan perkembangan tumor. Enzim deubiquitinasi
(DUBs) semakin diterima bahawa ia bermutasi pada kanser manusia dan mempunyai peranan sebagai onkogen dan penahan tumor.
Protein ubiquitination is a highly regulated process that controls multiple physiologically and pathologically relevant mechanisms involved in tumor development. There is growing recognition that mutated deubiquitinating enzyme (DUBs) in human cancers suggesting their roles as oncogenes and tumor suppressors.
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