Cloning And Overexpression Of Deoxyribonuclease (Nucb) From Bacillus Licheniformis In E. Coli Expression System

Leong , Xin Yun (2015) Cloning And Overexpression Of Deoxyribonuclease (Nucb) From Bacillus Licheniformis In E. Coli Expression System. Masters thesis, Universiti Sains Malaysia.

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Abstract

Deoksiribonuklease NucB daripada Bacillus licheniformis ATCC 14580 dijangka berpotensi menguraikan biofilem mikrob iaitu struktur biologi yang boleh menyebabkan banyak komplikasi buruk dalam konteks industri dan kesihatan kerana ia mempunyai 94% persamaan dengan B. licheniformis strain EI- 34-6 yang dipencil dari laut dan telah menunjukkan keupayaan untuk menguraikan biofilem yang dibentuk oleh kedua-dua golongan bakteria Gram-positif dan Gram-negatif dengan cepat. NucB deoxyribonuclease of Bacillus licheniformis ATCC 14580 is expected to disperse the microbial biofilm which is a problematic biological structure notorious for causing numerous complications in a variety of industrial and healthcare context due to its 94% similarity with that of the marine-isolated B. licheniformis strain EI-34-6 in which the latter has demonstrated the ability to rapidly break up the biofilms formed by both Gram-positive and Gram-negative bacteria.

Item Type:	Thesis (Masters)
Subjects:	R Medicine > R Medicine (General)
Divisions:	Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)) > Thesis
Depositing User:	Mr Noorazilan Noordin
Date Deposited:	07 Sep 2016 00:40
Last Modified:	12 Apr 2019 05:25
URI:	http://eprints.usm.my/id/eprint/30479

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