Synthesis And Activity Studies Of Novel Dispiro Pyrrolidine Compounds As Potential Antimycobacterial Agents

Ang , Chee Wei (2015) Synthesis And Activity Studies Of Novel Dispiro Pyrrolidine Compounds As Potential Antimycobacterial Agents. Masters thesis, Universiti Sains Malaysia.

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Abstract

Sekumpulan dispiro pirolidina yang mengandungi lima puluh dua sebatian telah berjaya disintesis dengan menggunakan penambahan siklo 1,3 dwikutub. Tindak balas ini terbukti sangat regioselektif, menghasilkan satu set regioisomer sahaja sebagai produk. A mini library of fifty two highly functionalized dispiro pyrrolidines were synthesized successfully using 1,3-dipolar cycloaddition. This reaction is proved to be highly regioselective, giving only one set of regioisomer as product.

Item Type: Thesis (Masters)
Subjects: R Medicine > R Medicine (General)
Divisions: Institut Penyelidikan Perubatan Molekul (Institute for Research in Molecular Medicine INFORMM) > Thesis
Depositing User: Mr Noorazilan Noordin
Date Deposited: 30 Aug 2016 04:56
Last Modified: 12 Apr 2019 05:25
URI: http://eprints.usm.my/id/eprint/30432

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