Murugaiyah, Vikneswaran
(2008)
Phytochemical, Pharmacological And Pharmacokinetic Studies Of Phyllanthus Niruri Linn Lignans As Potential Antihyperuricemic Agents [QK861. V694 2008 f rb].
PhD thesis, Universiti Sains Malaysia.
Abstract
Ekstrak metanol dari daun Phyllanthus niruri L. menunjukkan aktiviti antihiperurisemik oral yang bergantungan dos di dalam tikus hiperurisemia yang diaruh dengan kalium oksonat
dan asid urik.
The methanol extract from the leaves of Phyllanthus niruri L. showed dose-dependent oral antihyperuricemic activity in potassium oxonate- and uric acid-induced hyperuricemic rats.
Fractionation of the extract by resin chromatography gave a less polar fraction which exhibited the highest reduction of plasma uric acid.
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