Nageswararao, Meroshine (2025) Exploring Caspase-Independent Apoptosis Mechanism Of New -Carboline Derivatives In Chronic Myelogenous Leukemia. Masters thesis, Universiti Sains Malaysia.
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Abstract
Cancer is known as one of the serious causes of mortality among the world population. One of the most reliable treatments for cancer is chemotherapy, though drug resistance and severe side effects have caused major setbacks to effective treatment. Lately, it has been found that understanding the mechanism of action of a chemotherapy agent might lead to a more effective treatment for this disease which is named as targeted therapy. In the constant search for new anticancer agent alternatives, β-carboline alkaloids have been identified as good candidates for a new chemotherapy drug. β-carboline compounds M25, M56 and M62 were synthesised, and their purities were confirmed using gas chromatography-mass spectrometry (GC-MS) analysis
| Item Type: | Thesis (Masters) |
|---|---|
| Subjects: | Q Science |
| Divisions: | Pusat Racun Negara (National Poison Centre) > Thesis |
| Depositing User: | Mr Aizat Asmawi Abdul Rahim |
| Date Deposited: | 21 Jul 2026 08:18 |
| Last Modified: | 21 Jul 2026 08:18 |
| URI: | http://eprints.usm.my/id/eprint/64690 |
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