The Potential Role of Melatonin on Memory Function: Lessons from Rodent Studies

Zakaria, Rahimah and Ahmad, Asma Hayati and Othman, Zahiruddin (2016) The Potential Role of Melatonin on Memory Function: Lessons from Rodent Studies. Folia Biologica (Praha), 62. pp. 181-187. ISSN 2533-7602

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Pineal melatonin biosynthesis is regulated by the circadian clock located in the suprachiasmatic nucleus of the hypothalamus. Melatonin has been found to modulate the learning and memory process in human as well as in animals. Endogenous melatonin modulates the process of newly acquired information into long-term memory, while melatonin treatment has been found to reduce memory deficits in elderly people and in various animal models. However, the mechanisms mediating the enhancing effect of melatonin on memory remain elusive. This review intends to explore the possible mechanisms by looking at previous data on the effects of melatonin treatment on memory performance in rodents.

Item Type: Article
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences) > Article
Zoom Profil Pakar (Expert Profile) > Zahiruddin Othman (Medical Sciences)
Depositing User: Administrator Automasi
Date Deposited: 06 Sep 2019 08:23
Last Modified: 06 Sep 2019 08:23

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