Fasting plasma glucose as a screening test for gestational diabetes mellitus : a hospital-based, cross sectional study of 370 antenatal patients in Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia, 1999-2000

Mohd Noor, Nor Haznita (2002) Fasting plasma glucose as a screening test for gestational diabetes mellitus : a hospital-based, cross sectional study of 370 antenatal patients in Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia, 1999-2000. Masters thesis, Universiti Sains Malaysia.

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    Abstract

    Objektif: Mengkaji glukos plasma berpuasa (fasting plasma glucose) sebagai ujian penyaringan bagi penyakit kencing manis ketika mengandung (gestational diabetes mellitus). Objektif selanjutnya adalah untuk menentukan taburan demografi bagi penyakit kencing manis ketika mengandung dan menilai pecahan penyakit ini yang dapat dikesan melalui saringan selektif menggunakan faktor sejarak Metodologi: Kajian bersilang telah dijalankan di Hospital Universiti Sains Malaysia (HUSM), Kubang Kerian, Kelantan dari bulan Julai 1999 hingga bulan Oktober 2000. Data asas diambil daripada 461 pesakit yang bersetuju mengambil bahagian di dalam kajian ini, yang mana umur kandungannya tidak melebihi 28 minggu dan tidak mempunyai penyakit kencing manis sebelum ini. Ujian glukos piawai 2-jam 75-g telah dijalankan ke atas 370 pesakit. Penyakit kencing manis semasa mengandung dan subkategorinya iaitu kencing manis dan gangguan toleransi terhadap glukos semasa mengandung telah didefinasikan oleh mengikut 'Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Part 1 :Diagnosis and Classification of Diabetes Mellitus Provisional Report of a WHO Consultation'. Ciriciri saringan glukos plasma berpuasa dikaji melalui kiraan sensitiviti dan spesifisiti dengan 'receiver operator characteristic curves'. Objective: To evaluate fasting plasma glucose as a screening test for gestational diabetes mellitus. Further objectives were to determine demographic distribution of gestational diabetes mellitus and to assess the proportions of gestational diabetes mellitus picked up by selective screening using historical risk factors alone. Methods: A hospital-based, cross-sectional study was carried out at University Hospital, Universiti Sains Malaysia (HUSM), Kubang Kerian, Kelantan, from July 1999 till October 2000. Baseline data from 461 women who agreed to participate in the study with gestational ages less than 28 weeks and no previous diagnosis of diabetes were collected. A standardized 2-h 75-g oral glucose tolerance test was performed in 370 women. Gestational diabetes and its subcategories-diabetes and gestational impaired glucose tolerance-were defined according to the Definition, Diagnosis and Classification ofDiabetes Mellitus and its Complications. Part !:Diagnosis and Classification of Diabetes Mellitus Provisional Report of a WHO Consultation. Screening properties of fasting plasma glucose were evaluated by calculating sensitivity and specificity with receiver operator characteristic curves.

    Item Type: Thesis (Masters)
    Subjects: R Medicine > RG Gynecology and obstetrics
    Divisions: Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences)
    Depositing User: Mr Noorazilan Noordin
    Date Deposited: 05 Sep 2017 13:03
    Last Modified: 05 Sep 2017 13:09
    URI: http://eprints.usm.my/id/eprint/36368

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