Ang , Chee Wei
(2015)
Synthesis And Activity Studies Of Novel Dispiro Pyrrolidine Compounds As Potential Antimycobacterial Agents.
Masters thesis, Universiti Sains Malaysia.
Abstract
Sekumpulan dispiro pirolidina yang mengandungi lima puluh dua sebatian telah berjaya disintesis dengan menggunakan penambahan siklo 1,3 dwikutub. Tindak balas ini terbukti sangat regioselektif, menghasilkan satu set regioisomer
sahaja sebagai produk.
A mini library of fifty two highly functionalized dispiro pyrrolidines were synthesized successfully using 1,3-dipolar cycloaddition. This reaction is proved to
be highly regioselective, giving only one set of regioisomer as product.
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