Abdulla Alfadly, Saeed Obeid
(2007)
Pharmacokinetic Studies Of Ciprofloxacin And Theophylline And Of The Interaction Between These Two Drugs In Healthy Malaysian Volunteers [RM301.5. A135 2007 f rb].
PhD thesis, Universiti Sains Malaysia.
Abstract
Teofilin adalah sejenis bronkodilator yang kerap kali digunakan sebagai rawatan untuk penyakit asma dan halangan pernafasan kronik. Di dalam manusia dewasa, lebih kurang 90% teofilin dimetabolismekan di hati oleh enzim sitokrom P450 (CYP), dan hanya 10% dikumuhkan melalui ginjal dalam bentuk asal.
Theophylline is a bronchodilator frequently used in the treatment of asthma and chronic obstructive pulmonary disease. In human adults, approximately 90% of
theophylline is metabolised in the liver by the cytochrome P450 (CYP) enzymes, and only 10% is excreted via the kidneys in unchanged form.
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