Development Of Denaturing High Performance Liquid Chromatography (Dhplc) In Detection Of Common Polymorphisms In The Multi-Drug Resistance (MDR1) Gene Among Malay Patients With Leukemia [QH324.9.L5 B138 2006 f rb].

Yahaya, Badrul Hisham (2006) Development Of Denaturing High Performance Liquid Chromatography (Dhplc) In Detection Of Common Polymorphisms In The Multi-Drug Resistance (MDR1) Gene Among Malay Patients With Leukemia [QH324.9.L5 B138 2006 f rb]. Masters thesis, Universiti Sains Malaysia. .

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    Abstract

    Although the use of chemotherapy has evolved remarkably during the past 30 years for treatment in leukemia patients, it remains a difficult disease to treat where the main problem is drug resistance. This is due to over expression of multi-drug resistance gene (MDR1) and it’s over expression has been described in many tumors resistant to cytotoxic drugs including leukemias. Walaupun keberkesanan penggunaan kemoterapi dalam rawatan terhadap pesakit leukimia adalah jelas terbukti, namun leukimia tetap merupakan penyakit yang sukar dirawat terutamanya dalam masalah kerintangan pesakit terhadap ubat-ubatan (dadah).

    Item Type: Thesis (Masters)
    Subjects: Q Science > QH Natural history > QH301 Biology
    Divisions: Kampus Kesihatan (Medical Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences)
    Depositing User: ARKM Al Rashid Automasi
    Date Deposited: 24 Mar 2009 22:52
    Last Modified: 13 Jul 2013 11:56
    URI: http://eprints.usm.my/id/eprint/8626

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