Synthesis And Application Of Molecularly Imprinted Solid-Phase Extraction For The Determination Of Terbutaline In Biological Matrices [QD382.I43 L732 2006 f rb].

Lim, Lay Lee (2006) Synthesis And Application Of Molecularly Imprinted Solid-Phase Extraction For The Determination Of Terbutaline In Biological Matrices [QD382.I43 L732 2006 f rb]. Masters thesis, Universiti Sains Malaysia.

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    Abstract

    Kajian ini tertumpu kepada penilaian keberkesanan penggunaan MIPs sebagai bahan padatan dalam SPE untuk pengekstrakan terbutalina di dalam sampel plasma dan urin. Polimer ini dihasilkan dengan menggunakan asid metakrilik (MAA) sebagai monomer dan etilena glikol dimetakrilat (EGDMA) sebagai bahan silang manakala salbutamol dengan struktur yang hampir serupa dengan analit dipilih sebagai molekul templat. A study was performed to evaluate the feasibility of applying MIPs as sorbent material in SPE for clean up of terbutaline from urine and plasma samples. The imprinted polymer was prepared by using methacrylic acid (MAA) as functional monomer, ethylene glycol dimethacrylate (EGDMA) as cross-linker and salbutamol, a closely structural analogue to the targeted analyte as template molecule.

    Item Type: Thesis (Masters)
    Subjects: Q Science > QD Chemistry > QD241-441 Organic chemistry
    Divisions: Pusat Pengajian Sains Farmasi (School of Pharmacy)
    Depositing User: ARKM Al Rashid Automasi
    Date Deposited: 11 Mar 2009 21:47
    Last Modified: 13 Jul 2013 11:52
    URI: http://eprints.usm.my/id/eprint/8315

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