Low, Jen Hou
(2007)
Effect Of Rifampicin And Omeprazole In Combination With Chloroquine On Chloroquine Resistant Plasmodia In Vitro And In Vivo [RM666.C5215 L9 2007 f rb].
Masters thesis, Universiti Sains Malaysia.
Abstract
Kekebalan terhadap chloroquine telah mengakibatkan peningkatan
kematian dan morbiditi daripada penyakit malaria P. falciparum. Ketiadaan
vaksin yang berkesan mengakibatkan terapi malaria bergantung pada kombinasi
ubat alternatif seperti Mefloquine dan Artesunate dan tahap kekebalan terhadap
ubat-ubat alternatif tersebut kerap meningkat.
Chloroquine resistance has resulted in a resurgence of morbidity and
mortality from P. falciparum malaria. The lack of an effective vaccine forces
dependence on alternative drug combination therapies based on mefloquine or
artesunate, of which the incidence of multidrug resistance is steadily rising.
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