Effect Of Gelucire 44/14 On The Oral Bioavailability Of Cyclosporin A [RM666.C978 L73 2007 f rb ].

Lim, Sin Yee (2007) Effect Of Gelucire 44/14 On The Oral Bioavailability Of Cyclosporin A [RM666.C978 L73 2007 f rb ]. Masters thesis, Universiti Sains Malaysia.

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    Abstract

    Kajian ini dijalankan untuk mengkaji kesan Gelucire® 44/14 terhadap biokeperolehan oral bagi satu drug polipeptida lipofilik model, ciclosporin A. Formulasi Gelucire® 44/14 mengandungi ciclosporin A dengan nisbah drug kepada Gelucire® 44/14 1:4, 1:10, 1:14 dan 1:20 telah berjaya disediakan melalui teknik lebur-fusi. The present study was conducted to investigate the effect of Gelucire® 44/14 on the oral bioavailability of a model lipophilic polypeptide drug, cyclosporin A. Gelucire® 44/14 formulations of cyclosporin A at drug to Gelucire® 44/14 ratios of 1:4, 1:10, 1:14 and 1:20 (w/w) were successfully prepared using a heatfusion method.

    Item Type: Thesis (Masters)
    Subjects: R Medicine > RM Therapeutics. Pharmacology > RM300-666 Drugs and their actions
    Divisions: Pusat Pengajian Sains Farmasi (School of Pharmacy)
    Depositing User: ARKM Al Rashid Automasi
    Date Deposited: 26 Feb 2009 12:42
    Last Modified: 13 Jul 2013 11:49
    URI: http://eprints.usm.my/id/eprint/8135

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