Mohd Sani, Sa’udah Badriah (2025) Molecular And Cellular Analysis Of Hepg2 Hepatocellular Carcinoma Upon Deubiquitin Enzymes Otub1 And Otub2 Knockdown. Masters thesis, Universiti Sains Malaysia.
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Abstract
Hepatocellular carcinoma (HCC) is one of the most prevalent and deadly cancers worldwide. The deubiquitinating enzymes Otubain-1 (OTUB1) and Otubain-2 (OTUB2) have been linked to cancer progression, making them potential therapeutic targets. This study investigates the effects of OTUB1 and OTUB2 knockdown on cell viability, migration, and gene expression pathways in HepG2 cells, aiming to explore their roles in liver cancer.
| Item Type: | Thesis (Masters) |
|---|---|
| Subjects: | R Medicine > R Medicine (General) > R5-920 Medicine (General) |
| Divisions: | Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)) > Thesis |
| Depositing User: | Mr Aizat Asmawi Abdul Rahim |
| Date Deposited: | 19 Aug 2026 06:54 |
| Last Modified: | 19 Aug 2026 06:54 |
| URI: | http://eprints.usm.my/id/eprint/64799 |
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