Hassaan, Umar (2025) Development, Optimization And Characterization Of Cisplatin Loaded Cubosomes For Human Lung Carcinoma. PhD thesis, Universiti Sains Malaysia.
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Abstract
Lung cancer remains a major global health challenge due to the limitations of conventional therapies. Platinum-based chemotherapy, such as cisplatin, is widely used but hindered by systemic toxicity and rapid clearance. To address these issues, we developed a novel glyceryl monooleate (GMO)-based cubosomes platform for sustained cisplatin delivery, leveraging its unique bicontinuous lipid structure to overcome encapsulation and release limitations of existing nanocarriers like liposomes and polymeric nanoparticles.
| Item Type: | Thesis (PhD) |
|---|---|
| Subjects: | R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica |
| Divisions: | Pusat Pengajian Sains Farmasi (School of Pharmacy) > Thesis |
| Depositing User: | Mr Aizat Asmawi Abdul Rahim |
| Date Deposited: | 13 May 2026 06:25 |
| Last Modified: | 13 May 2026 06:25 |
| URI: | http://eprints.usm.my/id/eprint/64197 |
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