Intravenous Immunoglobulin Usage Among Patients In Hospital Kuala Lumpur

Zahari, Nurul Hidayah (2022) Intravenous Immunoglobulin Usage Among Patients In Hospital Kuala Lumpur. Masters thesis, Universiti Sains Malaysia.

[img] PDF
Download (3MB)

Abstract

Introduction: In the last decade, intravenous immunoglobulin (IVIG) has become widely used. This study focused on the characteristic of IVIG usage and associated factors towards the frequency status of IVIG among patients in Hospital Kuala Lumpur. Methods: A retrospective cross-sectional study was performed on 482 patients who received IVIG in Hospital Kuala Lumpur. Data were extracted from request form for IVIG recorded in the Pharmacy Department. Chi-square and T-test analysis were used for statistical analysis, a p-value of <0.05 was considered significant. Results: A total of 482 patients received IVIG in Hospital Kuala Lumpur from January 2018 until December 2019. There were 243 (50.4%) female and 228 (47.3%) males. The median age of the patients was 27 years old. The commonest indications for IVIG among all patients were hypogammaglobulinemia and other deficiency state, 127 patients (26.3%). Most common indication for one-off treatment in adult was hypogammaglobulinemia and other deficiency state, 72 patients (35.0%), whereas in paediatric was Kawasaki disease, 28 patients (20.3%). The commonest indication for regular therapy among adult patient was chronic inflammatory demyelinating polyneuropathy, 18 patients (23.4%) while in paediatric was sepsis, 19 patients (31.1%). Clinical category was associated with frequency status of IVIG usage in both adult and paediatric cohort with p = 0.004 and p = 0.017, respectively. Conclusion: There were significant differences between the indication for one-off treatment and regular therapy among adult and paediatric patients. Updated national guideline on the prescription of IVIG following evidenced based medicine for patients is needed to help clinicians in prescribing IVIG appropriately.

Item Type: Thesis (Masters)
Subjects: R Medicine
Divisions: Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)) > Thesis
Depositing User: NOR HASHIMY BIN ABDULLAH
Date Deposited: 16 Apr 2026 03:59
Last Modified: 16 Apr 2026 03:59
URI: http://eprints.usm.my/id/eprint/63924

Actions (login required)

View Item View Item
USM Repository is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.
Share