Sabri, Nurul Akmal (2025) Evaluation of phytochemicals, antioxidant & antimicrobial properties of cinnamomum verum extracts. Project Report. Universiti Sains Malaysia. (Submitted)
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Abstract
Traditional medicine has long relied on plant-based remedies to address various health issues, with cinnamon bark being widely recognized for its therapeutic properties. This study aims to investigate the phytochemical, antioxidant and antimicrobial properties of cinnamon extracts, emphasizing its potential as a natural therapeutic agent. Aqueous extract of C. verum (AECV) and ethanolic extract of C. verum (EECV) were analyzed for their bioactive compounds, revealing the presence of alkaloids, phenols, flavonoids, tannins, glycosides, and terpenoids, while saponins were detected only in AECV. Antioxidant activity was assessed using DPPH radical scavenging and total phenolic content (TPC) assays. AECV demonstrated higher antioxidant potential (IC50 = 0.233 mg/mL) than EECV (IC50 = 0.418 mg/mL), although both exhibited lower activity compared to ascorbic acid (AA) (IC50 = 0.00673 mg/mL). TPC analysis revealed that EECV (0.1001 [0.236] mg GAE/g) showed higher phenolic content than AECV (0.0227 [0.036] mg GAE/g), indicating ethanol's effectiveness in extracting phenolics. Antimicrobial activity against S. aureus and E. coli was evaluated using minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) assays, where AECV demonstrated limited antibacterial activity against S. aureus (MIC = 20 mg/mL), while EECV exhibited no significant effects. Neither extract inhibited E. coli, likely due to insufficient extract concentrations. These findings indicate that cinnamon bark showed potential as a natural source of antioxidant, while further investigation is needed to explore its antimicrobial potential
| Item Type: | Monograph (Project Report) |
|---|---|
| Uncontrolled Keywords: | Traditional medicine |
| Subjects: | R Medicine R Medicine > RA Public aspects of medicine > RA440-440.87 Study and teaching. Research |
| Divisions: | Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Kesihatan (School of Health Sciences) > Monograph |
| Depositing User: | MUHAMMAD AKIF AIMAN AB SHUKOR |
| Date Deposited: | 15 Dec 2025 06:53 |
| Last Modified: | 29 Dec 2025 07:19 |
| URI: | http://eprints.usm.my/id/eprint/63394 |
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