Xiaoping, Duan (2025) Retrospective study of risk factors for urethral stricture after transurethral resection of prostate among the elderly in Chengdu, China. Masters thesis, Universiti Sains Malaysia.
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Abstract
Benign prostatic hyperplasia (BPH) is becoming increasingly prevalent, and although transurethral resection of the prostate (TURP) remains the standard surgical treatment, late postoperative urethral stricture remains a potential complication. This cross-sectional study aimed to identify risk factors for urethral stricture following TURP. Clinical data from 400 BPH patients (mean age, 74.31 ± 6.70 years) who underwent TURP at Chengdu University Affiliated Hospital between June 2020 and June 2023 were retrospectively analyzed. This study divided the data into two groups: the urethral stricture group and the non-urethral stricture group. All data were analyzed using univariate and multivariate logistic regression analysis (P < 0.05 was set as the significance criterion). A total of 35 patients (8.75%) developed urethral stricture. Multivariate analysis identified age (OR = 1.121, 95% CI: 1.044–1.204, P = 0.002), prostate size (OR = 1.038, 95% CI: 1.014–1.062, P = 0.002), preoperative indwelling catheter (OR = 5.413, 95% CI: 1.872 – 15.655, P = 0.002), and postoperative indwelling catheter time (OR = 2.147, 95% CI: 1.405–3.280, P < 0.001) as independent risk factors for urethral stricture, whereas preoperative urethral dilation (OR = 0.049, 95% CI: 0.011–0.220, P < 0.001) was an independent protective factor. The nomogram prediction model established based on the above independent influencing factors (AUC = 0.916) has good application prospects in clinical diagnosis and risk assessment
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | - |
| Subjects: | R Medicine R Medicine > RA Public aspects of medicine |
| Divisions: | Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Kesihatan (School of Health Sciences) > Thesis |
| Depositing User: | MUHAMMAD AKIF AIMAN AB SHUKOR |
| Date Deposited: | 05 Nov 2025 02:22 |
| Last Modified: | 12 Nov 2025 08:29 |
| URI: | http://eprints.usm.my/id/eprint/63179 |
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